Editor's Choice - Our Favorite Python Aquarium Water Treatments

1. Python Multi-Purpose Water Conditioner, 67.6 oz

User Ratings: 85 2

Python 64WC First Impressions

"I was getting 30-40 ppm."

Way to go Fluval keep up the good WORK! During cycling you will be using often. It didn't kill the fish or cause any problems with the water so I stuck with it. I have a great pump and uv light but still had cloudy-ish water. Just an idea incase someone doesn't have a spare dropper. I've used every product on the market and this is the most AMAZING MUST HAVE PRODUCT! In my opinion there's nothing better.

• Python Multi-Purpose Water Conditioner, 67.6 oz
• Makes tap water safe for aquarium usage by neutralizing toxins
• Designed for use with freshwater and marine aquariums
• Herbal extracts help to calm fish and relieve stress
• 67.6 fl oz of solution treats 4.000 U.S. gal of aquarium water
• Part 1 of the Python three step water treatment system
• Manufacture: Python Products Inc.
• Product Dimensions: 8.4 x 3.4 x 6.8 inches; 1.2 Pounds

• Editor's Impressions Of The Python 64WC
• Treatment Effectiveness [star rating='5']
• Quality [star rating='4.9']
• Value For Money [star rating='4.2']
• Affordability [star rating='5']

Here Are Some Other Related Aquarium Water Treatments

2. AquaCura Praziquantel Fish Medicine – 50 grams - Ultra-Efficient Fish Flukes Treatment Powder for ...

User Ratings: 66 6

PRAZI-CURA BY AQUACURA First Impressions

"I was getting 30-40 ppm."

It only requires 3 drops per gallon you add to your tank. I have a great pump and uv light but still had cloudy-ish water. During cycling you will be using often. Thanks to the Amazon reviewer who mentioned this! My fish didn't appear negatively effected by it either. Crystal clear after changing water and adding this to my 2. Fish would die occassionally every few weeks or so.

• AquaCura Praziquantel Fish Medicine – 50 grams - Ultra-Efficient Fish Flukes Treatment Powder for Gold, Koi & Tropical Fish - Pond Water Conditioner for Freshwater & Saltwater - No Added Antibiotic
• KEEP YOUR FISH HEALTHY with a high-end Praziquantel fish treatment medication which will help combat conditions caused by external flukes, liver flukes, gill flukes, internal parasites, and internal worms.
• OFFER YOUR FISH A SAFE ENVIRONMENT: Excellent for goldfish, Koi and ornamental fish, the AquaCura Prazi fungus anti-parasite medication will eliminate pests from the fish pond, making it healthier for your fish.
• PRAZI_CURA IS VERY MILD ON YOUR FISH. Prazi-Cura is very mild on your fish, providing minimum impact on your prized fish while maximizing impact on parasitic infestations.
• INVEST IN AN EFFECTIVE WORMING AGENT: Complement your fish supplies with an ultra-efficient anti-parasite medication, which consists of genuine Praziquantel and contains zero added fillers and medicines.
• PROTECT YOUR FISH FROM PARASITES: Just add 1 gram of this fast-acting Prazi powder per every 100 gallons of your pond water to paralyze and kill worms, help the fish hosts shed them more easily and keep them safely away.
• Manufacture: Aquacura

• Editor's Impressions Of The PRAZI-CURA BY AQUACURA
• Treatment Effectiveness [star rating='3.8']
• Quality [star rating='4.4']
• Value For Money [star rating='4.3']
• Affordability [star rating='4.4']

3. ReefHD Reef Flux Anti-Fungal Bryopsis Treatment

User Ratings: 78 4

ReefHD First Impressions

"I was very surprised."

Ever since I made this purchase, my fish are not dying at all. The bottle will last me years as it is huge! Use a heater and crank it to 82 degrees again without fish in the tank. Fish are aerobic organisms that are susceptible to ROS. Beats the heck out of those expensive suit cleaners. Good Product, Good Price Gets five stars! I've used it for years with great results.

• ReefHD Reef Flux Anti-Fungal Bryopsis Treatment
• Manufacture: ReefHD
• Product Dimensions: 3 x 2 x 2 inches; 2 Ounces

• Editor's Impressions Of The ReefHD
• Treatment Effectiveness [star rating='5']
• Quality [star rating='4.5']
• Value For Money [star rating='4.8']
• Affordability [star rating='4']

4. API pH DOWN Freshwater Aquarium Water pH Reducing Solution 4-Ounce Bottle

User Ratings: 74 3

API 30C First Impressions

"I recommend it."

This water conditioner is a life saver! I used to use AmQuel years ago and then spent years out of the aquarium hobby. When they disinfect a repair site, they are normally only using chlorine. It took a couple of days to clear but it works. I read the instructions, measured out the product, and added it to the tank. Initially this was used as a sample packet came with our aquarium. Don't know if that made a difference but it didn't hurt.

• API pH DOWN Freshwater Aquarium Water pH Reducing Solution 4-Ounce Bottle
• Contains one (1) API pH DOWN Freshwater Aquarium Water pH Reducing Solution 4-Ounce Bottle
• Lowers freshwater aquarium water pH with a phosphate-free formula
• Does not promote algae growth with pH adjustments and is safe for plants and fish
• Slowly neutralizes alkaline substances that cause high water pH
• Test water weekly and use to correct pH level in freshwater aquariums
• This product contains 9.6% of sulfuric acid
• Manufacture: Aquarium Pharmaceuticals
• Product Dimensions: 1.5 x 1.5 x 5.25 inches; 4.8 Ounces

• Editor's Impressions Of The API 30C
• Treatment Effectiveness [star rating='3.9']
• Quality [star rating='4.2']
• Value For Money [star rating='3.7']
• Affordability [star rating='5']

5. DrTim's Aquatics Saltwater Clear-UP Natural Water Clarifier – for Fish Tanks, Aquariums, Water Fil...

User Ratings: 49

DrTim's Aquatics 244 First Impressions

"I am SO HAPPY!"

It's water change day so I did this step first then started cleaning the tank. The bottle will last me years as it is huge! I'm sold on this, I've tried SO MANY and wow. I read the instructions, measured out the product, and added it to the tank. This will give you how many drops is required per gallon. I'm sold on this, I've tried SO MANY and wow. During cycling you will be using often.

• DrTim's Aquatics Saltwater Clear-UP Natural Water Clarifier – for Fish Tanks, Aquariums, Water Filtering, Disease Treatment – Eco-Friendly Solution to Clear Waters – Removes Toxins – 32 Oz.
• THE BEST WAY TO SANITIZE A SALTWATER AQUARIUM: Produce crystal clear water when adding this Saltwater Clear-UP Natural Water Clarifier from DrTim’s Aquatics to your Saltwater fish tanks and aquariums.
• REMOVES HARMFUL TOXINS FROM SALTWATER FISH TANKS: The powerful results of this Saltwater Clear-UP Natural Water Clarifier are well beyond clear, H20 Pure water. Clear-UP adds beneficial bacteria to your fish tanks and flocs small particles from the water that cloud the Saltwater aquarium.
• 100% NATURAL, ECO-FRIENDLY FISH TANK CLEANER: Opt for an all-natural approach to revitalizing the water in your Saltwater fish tanks and aquariums with this solution that does not include any harmful chemicals or toxins.
• AQUARIUM SUPPLIES YOU NEED: Offer your pet fish and corals an environment in which they can thrive with this Clear-UP Natural Water Clarifier for Saltwater fish tanks and aquariums. Saltwater One & Only is available in quantities that include 4, 8, 16, 32, 64 and 128 ounces.
• HIGH-QUALITY AQUARIUM PRODUCTS: DrTim’s Aquatics offers an expansive line of aquarium products used by professionals and residential customers. Based on years of experience in marine biology, DrTim’s Aquatics’ products utilize his vast knowledge and are backed by scientific evidence and innovative research.
• Manufacture: DrTim's Aquatics, LLC
• Product Dimensions: 5 x 2 x 8 inches; 2 Pounds

• Editor's Impressions Of The DrTim's Aquatics 244
• Treatment Effectiveness [star rating='3.4']
• Quality [star rating='3.6']
• Value For Money [star rating='2.9']
• Affordability [star rating='3']

6. Instant Ocean Marine Conditioner 250 mL, Makes Tap Water Safe for Aquariums

User Ratings: 82

Instant Ocean IN05303 First Impressions

"I LOVE PRISTINE!"

Use a heater and crank it to 82 degrees again without fish in the tank. Fish are aerobic organisms that are susceptible to ROS. I know you are going to worry about your fish DON'T they are fine. I'm sold on this, I've tried SO MANY and wow. The top is a measuring tool as well which I was not expecting. I've used API water conditioner before and it works well. This is only temporary till I get a spare dropper.

• Instant Ocean Marine Conditioner 250 mL, Makes Tap Water Safe for Aquariums
• CONDITIONS WATER: Makes tap water safe for aquarium use – protects fish and promotes healthy water conditions.
• DETOXIFIES INSTANTLY: Eliminates heavy metals, chlorine and chloramine.
• FOR TANK MAINTENANCE: Use every time you add water to your aquarium.
• MEASURE: Use 5 mL for every 10 gallons of aquarium water.
• Manufacture: Instant Ocean
• Item Weight: 10.9 ounces
• Product Dimensions: 1.63 x 3 x 7 inches

• Editor's Impressions Of The Instant Ocean IN05303
• Treatment Effectiveness [star rating='3.8']
• Quality [star rating='4.4']
• Value For Money [star rating='5']
• Affordability [star rating='5']

7. RO/DI Reverse Osmosis Aquarium/Reef System Dual DI All Clear Manual Flush 75 GPD

User Ratings: 69 10

Fountainhead Water Systems First Impressions

"Tims bacteria."

However if you want a stress coat, this is perfect. It took a couple of days to clear but it works. I have two 36 gallon tanks right now. This is my go to water conditioner and stressed fish treatment. Easy to dispense the product without mess and easy to use per instructions. I didn't purchase this for an aquarium. If you have a freshwater fish tank, I highly recommend this product.

• RO/DI Reverse Osmosis Aquarium/Reef System Dual DI All Clear Manual Flush 75 GPD
• Type:Reverse Osmosis DI Unit, Country/Region Of Manufacture:United States
• Brand:Fountainhead Water Systems
• Mpn:FH32RODI75
• Manufacture: Fountainhead Water Systems
• Batteries Included?: No
• Batteries Required?: No

• Editor's Impressions Of The Fountainhead Water Systems
• Treatment Effectiveness [star rating='5']
• Quality [star rating='5']
• Value For Money [star rating='4.3']
• Affordability [star rating='3.9']

8. Tetra Correct pH Tablets - 24 Tablets Total (3 Packs with 8 Tablets per Pack)

User Ratings: 83 1

Tetra Tetra Correct pH Tablets - 24 Tablets To First Impressions

"It's CLEAR!"

My water was cloudy with a very fine misty haze. If you're treating injured fins or introducing new fish, this is for you. Do not clean the filters, do not change the filters. This is definitely worth trying if you have cloudy water. Fish seem healthy and active during use. If either or both ammonia and Nitrite are above 1ppm do not add ammonia. Pictures included to see the difference.

• Tetra Correct pH Tablets - 24 Tablets Total (3 Packs with 8 Tablets per Pack)
• Manufacture: United Pet Group
• Product Dimensions: 4 x 7 x 1 inches; 0.8 Ounces

• Editor's Impressions Of The Tetra Tetra Correct pH Tablets - 24 Tablets To
• Treatment Effectiveness [star rating='5']
• Quality [star rating='4.1']
• Value For Money [star rating='5']
• Affordability [star rating='5']

9. Natural Rapport Aquarium Water Conditioner - The Only All-in-1 Water Conditioner Fish Need - Natural...

User Ratings: 74 4

Natural Rapport First Impressions

"But that wasn't the case!"

It is just as good when compared to other brands of conditioner. Fish possess an antioxidant defense system to reduce the negative effects of ROS. I know you are going to worry about your fish DON'T they are fine. I like that it's a large bottle with multiple uses, so that's nice. We use it when we clean& change out water. Don't know if that made a difference but it didn't hurt. Ever since I made this purchase, my fish are not dying at all.

• Natural Rapport Aquarium Water Conditioner - The Only All-in-1 Water Conditioner Fish Need - Naturally Detoxifies and Removes Ammonia, Nitrite, Chlorine, and Chloramine (16 fl oz.)
• PROFESSIONAL GRADE CONDITIONER - For Your Freshwater and Saltwater aquariums. No need for separate steps, supplies, accessories, or chemical kits to treat API stress coats, slime coats. Our professional chlorine remover does it all in one step.
• SALT & FRESHWATER - Treatments during changes will help your betta, goldfish, or others thrive as it balances pH, adds electrolytes, slime and stress coats for your fish. Also safer for saltwater marine invertebrates, plants and crustaceans.
• DETOXIFIES & REMOVES HARMFUL CHEMICALS - Quick to remove harmful bacteria such as Ammonia, Nitrate, Chlorine, Chloramine, Heavy Metals, and more. Our 'Natural Choice' Dechlorinator and clarifier does all this plus is safer for your aquarium.
• ALL-IN-ONE CONDITIONER - Makes your tap water instantly safe by removing harsh chemicals and detoxifies heavy metals. is so effective and safe it is also recommended for aqua live reefs. From beta fish to exotics, our treatment is great for all.
• 100% SATISFACTION GUARANTEED - Made in the USA, with a 100% Satisfaction Guarantee. We are a family-owned business passionate about making wholesome, natural products to keep your beautiful fresh- or sea salt-water fish safer and tanks healthier.
• Manufacture: Natural Rapport
• Product Dimensions: 3 x 3 x 8 inches; 1.2 Pounds

• Editor's Impressions Of The Natural Rapport
• Treatment Effectiveness [star rating='4.5']
• Quality [star rating='3.9']
• Value For Money [star rating='5']
• Affordability [star rating='4.5']

10. Tetra AquaSafe Plus Water Conditioner/Dechlorinator

User Ratings: 82 1

Tetra 16268 First Impressions

"Mostly for betta's."

It is much safer to simply to add 3 drops per gallon. You need a source of ammonia to feed the bacteria which Dr. API Stress Coat is a phenomenal product. Beats the heck out of those expensive suit cleaners. Just an idea incase someone doesn't have a spare dropper. Thanks to the Amazon reviewer who mentioned this! Way to go Fluval keep up the good WORK!

• Tetra AquaSafe Plus Water Conditioner/Dechlorinator
• FOR FRESHWATER AND MARINE aquariumS: Tetra AquaSafe Plus works instantly to make tap water safe for fish.
• ADVANCED FORMULA: Neutralizes or removes harmful chlorine, chloramines and heavy metals.
• PROTECTS FISH: Enhances protective slime coat to help wounds heal.
• CLEAR AND HEALTHY WATER: With natural biopolymers and essential vitamins and minerals.
• WATER CONDITIONER: Use when setting up a new aquarium, with monthly partial water changes, or evaporation replacement.
• NEW LOOK: Packaging may vary
• The added ingredients help to reduce aquarium pollution
• Manufacture: Tetra
• Product Dimensions: 2 x 2 x 6.75 inches; 11.36 Ounces

• Editor's Impressions Of The Tetra 16268
• Treatment Effectiveness [star rating='4.4']
• Quality [star rating='4']
• Value For Money [star rating='5']
• Affordability [star rating='4.5']